What are Isoflavones?

Isoflavones or phytoestrogen are plant based compounds that can mimic the effects of oestrogen in our bodies. They have a similar structure to oestrogen which allows them to bind with oestrogen receptors which are located throughout our bodies. 

You can find phytoestrogens naturally in foods like soybeans, chickpeas, lentils & other legumes and this is probably the healthiest way to increase consumption of phytoestrogens.

There is also some evidence of other health benefits when these foods are eaten regularly.

They are thought to be anti-inflammatory and antioxidant and some studies have suggested that they may help to prevent heart disease and have cancer fighting properties. 

As well as being found naturally in some foods they are also commonly marketed as supplements in various forms and dosages which can make their safety uncertain when taken in this way. 

During the last few years phytoestrogens have become popular due to their potential health benefits in relation to menopausal symptoms and some women do take them as a natural alternative to HRT.

According to NICE (National Institute for clinical excellence) there is some evidence that phytoestrogen supplements can relieve vasomotor symptoms (hot flashes) however they say that their safety is uncertain and that interactions with other medicines have been reported.

A study in the Journal of the American Medical association (2016) looked at 60 studies and found that isoflavones  provided a modest reduction in hot flashes and vaginal dryness, but were not effective for reducing hot sweats at night. 

Drug interactions

You should be aware that there are some potential drug interactions when taking phytoestrogens or eating large amounts of soy products including blood thinning medications such as warfarin or aspirin, thyroid medications, some antibiotics and also some diabetes medications. 

If you are considering taking a supplement please take advice from a medical practitioner especially if you are taking any other medications. Unlike prescribed medication, supplements have not been rigorously researched and tested and therefore should always be treated with caution.

If you do want to try using soy products naturally from foods, introduce them slowly as they can cause gastrointestinal upsets such as constipation, bloating and nausea.

In summary, whilst isoflavones may offer a natural alternative to HRT for menopausal women there is currently no convincing evidence of their effectiveness and you should consider carefully the risks and benefits in light of your individual health needs and medical history